Quinolones Top Market Review and Current Demand - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2018 - 2025
Press
Release - 02 Feb 2018 Global Research and Development News
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Report
Description-
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Antibacterial
drugs are classified into ?-lactams, macrolides, tetracyclines,
aminoglycosides, sulfonamides, phenicols, quinolones, and
miscellaneous antibacterial drugs. Quinolones is a major class of
antibacterial drugs. Quinolones/fluoroquinolones are synthetic
antibacterial drugs that exhibit a specific function of inhibiting
the nucleic acid synthesis. Depending on their bactericidal
properties, quinolones are effective against bacterial infections of
the skin, the sinuses, the lungs, the stomach, and the urinary tract.
With their property of inhibiting the nucleic acid synthesis, these
drugs can interfere with the human DNA synthesis, as humans have the
same basic nucleic acid constituents as those of bacteria. Quinolones
exhibit rapid bactericidal activity, wherein they easily penetrate
the bacterial cell membrane and reach the DNA where they bind to
bacterial topoisomerases such as DNA gyrase, thereby inhibiting the
bacterial nucleic acid synthesis.
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There
have been side-effects associated with the use of quinolones, due to
which some of the drugs such as Tequin (gatifloxacin) manufactured by
Bristol-Myers Squibb have been withdrawn from the market in a very
short span after their launch (in 2006). According to the United
States Food & Drug Administration (U.S. FDA), Tequin was
discontinued due to adverse reactions in 2.7% of more than 5,000
treated patients. Some of the first-generation quinolones include
nalidixic acid and cinoxacin. Also, nalidixic acid was among the
first quinolone drugs that were utilized for treating urinary tract
infections way back in 1962. Quinolones exhibit significant
bactericidal activity and hence, they have been widely utilized in
treating bacterial infections of the skin, the sinuses, the lungs,
the stomach, and the urinary tract.
Key driver for the quinolones/fluoroquinolones
market is the increasing prevalence of infectious diseases led by
emergence of various mutant bacterial strains worldwide. Other
drivers include increasing occurrence of multi-drug resistant forms
of bacteria, which raises health care concerns and thereby, provides
ample growth opportunities to drug manufacturers. Due to their
numerous benefits over other antibacterial drugs, quinolones may
replace other drug therapies to some extent. These beneficial
characteristics include good oral absorption, easier tissue
penetration, lower side-effects, easier dosage of once or twice a
day, and a broad-spectrum activity against several pathogenic
bacterial strains. However, patent expiries of leading antibacterial
drugs of this class, narrow product pipeline, and availability of
different generic drugs may restrain the quinolones market in the
near future.
Some of the most widely used quinolones available
for human use are norfloxacin (the first quinolone approved in 1986)
and ciprofloxacin (approved in 1987). Other important quinolones
include ofloxacin (1990), enoxacin (1991), lomefloxacin (1992),
levofloxacin (1996), trovafloxacin (1997), gatifloxacin (1999), and
moxifloxacin (1999). The leading branded drugs available in the
global quinolones market are Avelox/Avalox (moxifloxacin),
Cipro/Ciprobay (ciprofloxacin), Zymaxid (gatifloxacin), Levaquin, and
Tavanic (levofloxacin).
The global quinolones market can be segmented
based on type, distribution channel, and region. Based on type, the
market can be divided into norfloxacin, ofloxacin, ciprofloxacin,
levofloxacin, gemifloxacin, grepafloxacin, gatifloxacin,
sparfloxacin, enoxacin, and moxifloxacin. Based on distribution
channel, the global quinolones market has been segregated into
hospital pharmacies, retail pharmacies, and online pharmacies.
Geographically, the global quinolones market can be segmented into
five key regions viz. North America, Europe, Asia Pacific, Latin
America, and Middle East & Africa. North America and Asia Pacific
hold a leading share of the global quinolones market. Increasing
prevalence of infectious diseases in developing countries offers
immense growth opportunities to the quinolones market in these
countries.
Key players operating in the global quinolones
market are Bayer AG, Sanofi, Johnson & Johnson, Merck & Co,
Inc., LG Life Sciences, Allergan, Inc., and Novartis AG.
The report offers a comprehensive evaluation of
the market. It does so via in-depth qualitative insights, historical
data, and verifiable projections about market size. The projections
featured in the report have been derived using proven research
methodologies and assumptions. By doing so, the research report
serves as a repository of analysis and information for every facet of
the market, including but not limited to: Regional markets,
technology, types, and applications.
The study is a source of reliable data on:
- Market segments and sub-segments
- Market trends and dynamics
- Supply and demand
- Market size
- Current trends/opportunities/challenges
- Competitive landscape
- Technological breakthroughs
- Value chain and stakeholder analysis
The regional analysis covers:
- North America (U.S. and Canada)
- Latin America (Mexico, Brazil, Peru, Chile, and others)
- Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, and Luxembourg)
- Eastern Europe (Poland and Russia)
- Asia Pacific (China, India, Japan, ASEAN, Australia, and New Zealand)
- Middle East and Africa (GCC, Southern Africa, and North Africa)
The report has been compiled through extensive
primary research (through interviews, surveys, and observations of
seasoned analysts) and secondary research (which entails reputable
paid sources, trade journals, and industry body databases). The
report also features a complete qualitative and quantitative
assessment by analyzing data gathered from industry analysts and
market participants across key points in the industry’s value
chain.
A separate analysis of prevailing trends in the
parent market, macro- and micro-economic indicators, and regulations
and mandates is included under the purview of the study. By doing so,
the report projects the attractiveness of each major segment over the
forecast period.
Highlights of the report:
- A complete backdrop analysis, which includes an assessment of the parent market
- Important changes in market dynamics
- Market segmentation up to the second or third level
- Historical, current, and projected size of the market from the standpoint of both value and volume
- Reporting and evaluation of recent industry developments
- Market shares and strategies of key players
- Emerging niche segments and regional markets
- An objective assessment of the trajectory of the market
- Recommendations to companies for strengthening their foothold in the market
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Clear Details get Table of Contents
https://www.researchmoz.us/quinolones-market-global-industry-analysis-size-share-growth-trends-and-forecast-2017-2025-report.html#table-of-content
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