Asia-Pacific Research on Asthma Therapeutics Markets to 2023 - High Prevalence and Highly Priced Existing & Upcoming Biologics will Drive the Market
"Asthma
Therapeutics in Asia-Pacific Markets to 2023 - High Prevalence and
Highly Priced Existing & Upcoming Biologics will Drive the
Market"
The Report covers current Industries Trends, Worldwide Analysis,
Global Forecast, Review, Share, Size, Growth, Effect.
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Description-
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Asthma is a common chronic inflammatory disease of the airways,
characterized by recurrent attacks of breathlessness and wheezing,
which vary in frequency and severity from patient to patient. The
exact causes of asthma are currently unknown, and may be the result
of a combination of factors, although two major factors thought to be
involved are environmental exposure and host factors, particularly
genes. The disease has significant global incidence and there is
currently no cure. Pharmacotherapeutic intervention aims to provide
patients with an increased level of disease control and reduce the
severity of symptoms, and a number of inhalational therapeutic
options are available.
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Asthma
treatment can be classed as either long-term control medication,
aimed at controlling persistent asthma, or quick-relief medication,
for the relief of exacerbations and acute symptoms. Long-term control
medication includes inhaled corticosteroids (ICS), immunomodulators,
leukotriene modifiers, cromolyn sodium, nedocromil and
methylxanthines. In addition, long-acting beta-adrenoceptor agonists
(LABA) can be used in combination with ICSs - but not as
monotherapies - for moderate or severe persistent asthma. Currently,
only two biologics - Xolair (omalizumab) and Nucala (mepolizumab) -
are approved as add-on therapy for the treatment of allergic and
severe refractory eosinophilic asthma in the Asia-Pacific region.
Unmet need therefore remains in the form of patients that do not
respond well to current therapeutics.
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The Asia-Pacific asthma market was
valued at $4.1 billion in 2016. The large size of the market is
driven by high prevalence rates, particularly among children and the
aging population; the need for long-term reliever and maintenance
medication; and the expected launch of high-cost biological
therapies.
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-- Scope--
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The current asthma market in the Asia-Pacific
region contains novel products, including Xolair, a recombinant
humanized monoclonal anti-IgE antibody; Seretide/Adoair, an ICS-LABA
combination therapy; Relvar/Breo, another ICS-LABA combination
therapy; and Spiriva, a LAMA.
- What are the competitive advantages of the existing novel drugs?
With over 290 active pipeline molecules, most of the late-stage investigational drug candidates offer improved dosing regimens and administration routes in comparison to currently marketed products.
- Which classes of novel drugs are most prominent within the pipeline?
- How much potential is there for the pipeline to address unmet needs within the asthma market?
Analysis of clinical trials since 2006 has identified that the failure rates of asthma molecules were highest in Phase III (60%).
- How do failure rates vary by product stage of development, molecule type, and mechanism of action?
- How do other factors, such as average trial duration and trial size influence the costs and risks associated with product development?
Over the 2016-2023 forecast period the asthma therapeutics market in the Asia-Pacific region is expected to increase in value at a compound annual growth rate of 5.4%, from $4.1 billion to over $6 billion.
- Which markets make the most significant contribution to the current market size?
- What are the epidemiology trends in these markets?
- Will new market entrants lead to substantial changes in annual therapy costs?
- How will different treatment usage patterns impact growth in the five assessed Asia-Pacific markets?
- What are the competitive advantages of the existing novel drugs?
With over 290 active pipeline molecules, most of the late-stage investigational drug candidates offer improved dosing regimens and administration routes in comparison to currently marketed products.
- Which classes of novel drugs are most prominent within the pipeline?
- How much potential is there for the pipeline to address unmet needs within the asthma market?
Analysis of clinical trials since 2006 has identified that the failure rates of asthma molecules were highest in Phase III (60%).
- How do failure rates vary by product stage of development, molecule type, and mechanism of action?
- How do other factors, such as average trial duration and trial size influence the costs and risks associated with product development?
Over the 2016-2023 forecast period the asthma therapeutics market in the Asia-Pacific region is expected to increase in value at a compound annual growth rate of 5.4%, from $4.1 billion to over $6 billion.
- Which markets make the most significant contribution to the current market size?
- What are the epidemiology trends in these markets?
- Will new market entrants lead to substantial changes in annual therapy costs?
- How will different treatment usage patterns impact growth in the five assessed Asia-Pacific markets?
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-- Reasons to buy--
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- Understand the clinical context of asthma by
considering symptoms, etiology, pathophysiology, epidemiology,
diagnosis, and treatment options.
- Identify the therapeutic strategies, products, and companies that dominate the current marketed products landscape, and recognize gaps and areas of unmet need.
- Identify key pipeline trends in molecule type, administration route, mechanism of action and novelty. Analyze the asthma pipeline and stratify pipeline therapies by stage of development, molecule type and molecular target. There are signs in the pipeline that the industry is seeking novel approaches to meet unmet needs within asthma.
- Consider market opportunities and potential risks by examining trends in asthma clinical trial size, duration, and failure rate by stage of development, molecule type, and mechanism of action.
- Recognize the late-stage pipeline molecules that have demonstrated strong therapeutic potential in asthma by examining clinical trial data and multi-scenario product forecast projections.
- Compare treatment usage patterns, annual therapy costs, and market growth projections for China, India, Australia, South Korea and Japan.
- Discover trends in licensing and co-development deals concerning asthma products and identify the major strategic consolidations that have shaped the commercial landscape.
- Identify the therapeutic strategies, products, and companies that dominate the current marketed products landscape, and recognize gaps and areas of unmet need.
- Identify key pipeline trends in molecule type, administration route, mechanism of action and novelty. Analyze the asthma pipeline and stratify pipeline therapies by stage of development, molecule type and molecular target. There are signs in the pipeline that the industry is seeking novel approaches to meet unmet needs within asthma.
- Consider market opportunities and potential risks by examining trends in asthma clinical trial size, duration, and failure rate by stage of development, molecule type, and mechanism of action.
- Recognize the late-stage pipeline molecules that have demonstrated strong therapeutic potential in asthma by examining clinical trial data and multi-scenario product forecast projections.
- Compare treatment usage patterns, annual therapy costs, and market growth projections for China, India, Australia, South Korea and Japan.
- Discover trends in licensing and co-development deals concerning asthma products and identify the major strategic consolidations that have shaped the commercial landscape.
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