Early Toxicity Testing In-Depth Industrial and Market studies - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2016 - 2019
Albany, New York, Jan 23,2017
"Early
Toxicity Testing Market - Global Industry Analysis, Size, Share,
Growth, Trends and Forecast, 2016 - 2019"
The Report covers current Industries Trends, Worldwide Analysis,
Global Forecast, Review, Share, Size, Growth, Effect.
Description-
Toxicity
is an extent to which a particular substance can damage the living
organism; it is important parameter to be evaluated during all stages
of drug development. Toxicity is one of the major reasons for failure
of drug development and rejection of drug candidate. Toxicity can be
because of dosage, form, half life and other parameters of drug.
Since long time toxicity is measured at the later stage of the drug
development process but considering higher rejection rate of drug in
recent years citing high toxicity level and cost impact of later
stage failure, companies started early toxicity testing and taken
measures accordingly to reduce the attrition rate in drug discovery.
Early
toxicity testing can be of three types namely in vivo, in vitro and
in silico. In vivo toxicity testing is performed on living animals,
in in vitro technique testing is performed in laboratories using
biochemical assays and cellular assays without animals whereas in in
silico technique testing is done by data analysis on computer with
the help of data mining and data modeling tools. Out of all these
techniques, there are significant advancements happened in in vivo
technique; while other two techniques are still in development stage.
According to industry leader, cost of drug those get rejected because
of late toxicity is 40% of overall drug development spending, where
there is around USD 50 billion spend on drug development put
together. Many organizations which are working towards environment
and animal protection are opposing in vivo approach, and are
pressurizing governments to make companies opt for in silico
approach. Several initiatives such as FDA’s Critical Path
Initiative and the European Union’s Seventh Research Framework
Programme are aimed at improving toxicity evaluation process during
drug development stages.
Therefore
in coming years there may be considerable shift of paradigm from in
vivo to in vitro and in silico. There are some studies conducted for
usage of nanoparticles in toxicological testing, along with this
developments are also in progress for producing 3 dimensional human
tissues for toxicity testing. Organovo is one of the players focused
on replacing animal testing and biological assays by producing model
of human liver. This model mimics the form and functions of human
liver and therefore can be used for toxicological testing.
Early
toxicity testing market can be segmented in various categories such
as on the basis of regional geography, approach of technique and
according to market share by major companies. According to technical
approach early toxicity testing market is segmented in in vivo, in
vitro and in silico, among all these in vivo market contributing
highest followed by in vitro and in silico. Pharmaceutical companies,
chemical companies and companies related to food products are main
customers for early toxicity detection testing players.
Some
of the market players in this industry segment are Accelrys, BD
Biosciences, Beckman Coulter, Inc., Charles River Laboratories, Gene
Logic, Invitrogen, Covance, IDBS, Thermo Fisher.
–
This research report analyzes this market depending on its
market segments, major geographies, and current market trends.
Geographies analyzed under this research report include
- North America
- Asia Pacific
- Europe
- Rest of the World
– This
report provides comprehensive analysis of
- Market growth drivers
- Factors limiting market growth
- Current market trends
- Market structure
- Market projections for upcoming years
This report is a
complete study of current trends in the market, industry growth
drivers, and restraints. It provides market projections for the
coming years. It includes analysis of recent developments in
technology, Porter’s five force model analysis and detailed
profiles of top industry players. The report also includes a review
of micro and macro factors essential for the existing market players
and new entrants along with detailed value chain analysis.
– Reasons
for Buying this Report
- This report provides pin-point analysis for changing competitive dynamics
- It provides a forward looking perspective on different factors driving or restraining market growth
- It provides a six-year forecast assessed on the basis of how the market is predicted to grow
- It helps in understanding the key product segments and their future
- It provides pin point analysis of changing competition dynamics and keeps you ahead of competitors
- It helps in making informed business decisions by having complete insights of market and by making in-depth analysis of market segments
- It provides distinctive graphics and exemplified SWOT analysis of major market segments
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